Intersegmental interaction of systems of presynaptic inhibition in a spinal cord


  • O. O. Shugurov Oles Honchar Dnipropetrovsk National University

Abstract

In this message the effect of stimulation of nearest dorsal roots in segments L5 – L7 of spinal cord on N1 and P components of the cord dorsum potential is described. The changes of these components at simultaneous stimulation of dorsal roots and at the “moved in time” stimulation are shown. We point that such spatial zones of activity of N1-component neurons are independent, but the same zones for the neurons of substantia gelatinosa overlap. The causes of such spatial property of neurons of spinal cord are considered.

References

Шугуров О. О. Критерии дивергентно-конвергентных отношений в моносинаптических нейронных системах спинного мозга // Биол. вестник (ХНУ). – 2007. – Т. 11, № 2. – С. 30–35.
Brown A. G. The dorsal horn of the spinal cord // J. Exp. Physiol. – 1982. – Vol. 67, N 1. – P. 193–212.
Carlton S. M. Peripheral GABAA receptors: evidence for peripheral primary afferent depolarization / S. M. Carlton, S. Zhou, R. E. Coggeshall // Neuroscience. – 1999. – Vol. 93, N 2. – P. 713–722. >> doi.:10.1016/S0306-4522(99)00101-3
Cervero F. The substanta gelatinosa of the spinal cord. A critical review / F. Cervero, A. Iggo // Brain. – 1980. – Vol. 103, N 4. – P. 717–772. >> doi.:10.1093/brain/103.4.717
Koerber H. R. Morphology of functional long-ranging primary afferent projections in the cat spinal cord / H. R. Koerber, K. Mirnics // J. Neurophysiol. – 1995. – Vol. 74, N 6. – P. 2336–2348.
Lidierth M. Dorsal horn cells connected to the Lissauer tract and their relation to the dorsal root potential in the rat / M. Lidierth, P. D. Wall // J. Neurophysiol. – 1998. – Vol. 80, N 2. – P. 667–679.
Manjarrez E. Intersegmental synchronization of spontaneous activity of dorsal horn neurons in the cat spinal cord / E. Manjarrez, I. Jimenez, P. Rudomin // Exp. Brain Res. – 2003. – Vol. 148. – P. 401–413.
Melnick I. M. Ionic basis of tonic firing in spinal substantia gelatinosa neurons of rat / I. M. Melnick, S. F. A. Santos, K. Szokol // J. Neurophysiol. – 2004. – Vol. 91, N 1. – Р. 646–655.
Statistical analysis of ongoing activity of neurones in the substantia gelatinosa and in lamina III of cat spinal cord / W. M. Steedman, A. Iggo, V. Molony et al. // Quarterly J. Exp. Physiol. – 1983. – Vol. 68. – P. 733–746. >> doi.:10.1113/expphysiol.1983.sp002762
Steedman W. M. The influence of cutaneous inputs on the activity of neurones in the substantia gelatinosa / Processing of sensory information in the superficial dorsal horn of the spinal cord // Ed. by F. Cervero. – New York : Plenum press, 1989. – P. 145–158. >> doi.:10.1007/978-1-4613-0825-6_17
Substantia gelatinosa neurons in the medullary dorsal horn: an intracellular labeling study in the rat / Y.-Q. Li, H. Li, T. Kaneko, N. J. Mizuno // J. Comp. Neurol. – 1999. – Vol. 411, N 3. – P. 399–412. >> doi.:10.1002/(SICI)1096-9861(19990830)411:3%3C399::AID-CNE4%3E3.0.CO;2-6
>>doi.:10.1002/(SICI)1096-9861(19990830)411:3%3C399::AID-CNE4%3E3.3.CO;2-Y
Sugiura Y. Difference in distribution of cenral terminals between visceral and somatic unmyelinated (C) primary afferent fibers / Y. Sugiura, T. Naohito, H. Yasahiko // J. Neurophysiol. – 1989. – Vol. 62, N 4. – P. 834–840.
Wall P. D. Excitability changes in afferent fibre termination and their relation to slow potentials // J. Physiol. (Lond.). – 1958. – Vol. 142, N 1. – P. 1–21. >> doi.:10.1113/jphysiol.1958.sp005997
Wall P. D. Five sources of a dorsal root potential: their interactions and origins in the superficial dorsal horn / P. D. Wall, M. Lidierth // J. Neurophysiol. – 1997. – Vol. 78, N 2. – Р. 860–871.
Yoshimura M. Membrane properties of rat substantia gelatinosa neurons in vitro / M. Yoshimura, T. M. Jessell // J. Neurophysiol. – 1989. – Vol. 62, N 1. – P. 109–118.
Yoshimura M. Primary afferent evoked synaptic responses and slow potential generation in rat substantia gelatinosa neurons in vitro / M. Yoshimura, T. M. Jessell // J. Neurophysiol. – 1989. – Vol. 62, N 1. – P. 96–108.
Published
2009-01-22
Section
Articles