Changes of the pain level under metallotionein-II effect


  • O. A. Kruchinenko Oles Honchar Dnipropetrovsk National University
  • G. А. Ushakova Oles Honchar Dnipropetrovsk National University

Abstract

It was studied the effect of metallotionein-II to rats under postoperative somatogenic pain conditions. The main mechanism of pain is excitement of the glutamate receptors. The data obtained allow to suggest that decrease of postoperative hyperalgesia under metallotionein-ЇІ effect is connected with binding of the zink ions that stimulate NMDA-receptors.

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Published
2005-01-25
Section
Articles